Vitamin D

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Sun exposure lowers cancer risk

2012 May 14 by

A study that correlated exposure to sunlight with cancer risk found that people exposed to more sunlight had a significantly lower risk of many types of cancer (Lin, 2012). This study followed more than 450,000 white, non-Hispanic subjects aged 50-71 years from diverse geographic areas in the US. Researchers correlated the calculated ultraviolet radiation (UVR) exposure in these different areas with the incidence of a variety of cancers. The diverse sites included six states (California, Florida, Louisiana, New Jersey, Pennsylvania, and North Carolina), and the metropolitan areas of Atlanta and Detroit. They followed these subjects over a period of nine years in the study and eliminated other known risk factors for cancer such as smoking, body mass index, and physical activity. This was the first prospective study (participants were actively observed for the duration of the study) to look at the relationship of sunlight to cancer.

Less sun more cancer

A total of 75,000 participants in the study contracted cancer. The study found that 12 types of cancer were reduced in those subjects exposed to more sunlight. These included cancers of the lungs, prostate, pancreas, colon, thyroid and many other types. As expected, melanoma and other skin cancers occurred more often in the participants exposed to more sunlight. The incidence of cancers of female organs including the ovaries, breast, and uterus were not reduced in this study, possibly because men spend more time outdoors than women. This confirmed a previous study that showed a decreased incidence of cancer in men but not women in relation to sun exposure (Grant, 2012).

Cancer prevention formula: sunlight, vitamin D, and antioxidants

This research confirms the protective effect of Vitamin D for many types of cancer. No other known factors in sun exposure would account for these findings. This provides more evidence that sun exposure is protective and that the routine use of sunscreens is counterproductive. Sunscreen should be used to prevent sunburn during prolonged exposure to bright sun at midday. And only zinc oxide sunscreens are safe. Eating organic fresh fruits and vegetables rich in antioxidants will also help prevent sunburn and protect you from skin cancer. Sun exposure and ultraviolet radiation promote health and prevent cancer. Similarly, in parts of the world and times of the year with limited sun exposure taking a vitamin D supplement in adequate amounts is beneficial to the immune system, promotes bone growth, prevents cardiovascular disease, and reduces the incidence of cancer.

References

Grant WB. An ecological study of cancer mortality rates in California, 1950–64, with respect to solar UVB and smoking indices. Dermatoendocrinol., epub April 2012

Lin SW, Wheeler DC, Park Y, Cahoon EK, Hollenbeck AR, Michal Freedman D, Abnet CC. Prospective study of ultraviolet radiation exposure and risk of cancer in the U.S. Int J Cancer. 2012 Apr 26. doi: 10.1002/ijc.27619.

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Taking Vitamin D During Pregnancy

2012 April 9 by

Vitamin D prevents language problems

A study published in the March 2012 issue of Pediatrics, the journal of the American Association of Pediatrics, has shown again how important vitamin D3 supplementation is during pregnancy (Whitehouse, 2012). This study measured the vitamin D level of pregnant women and then observed language development in their children at different ages (2, 5, 8, 10, 14, and 17 years of age).

The study found that women who had a vitamin D level less than 46 nmol/L during pregnancy were at least twice as likely to have children with language difficulties at ages 5 and 10 years compared to women with a vitamin D level of 70 nmol/L or higher.

This finding is especially interesting because most labs place the normal limit of serum 25(OH)-vitamin D in the 30 range, rather than the 70 range. Many vitamin D experts have said that a range of 60 to 100 is ideal, and this study suggests that at least during pregnancy these higher levels of vitamin D are ideal. In order to achieve these levels pregnant women need to take a significantly higher level of vitamin D3 than is found in most prenatal or calcium supplements. A supplement in the range of 5,000 to 10,000 IU of vitamin D3 daily is usually required to raise serum vitamin D levels to these levels.

Vitamin D prevents respiratory problems

Vitamin D taken during pregnancy has shown other benefits for later childhood as well. Several studies have shown that higher vitamin D levels during pregnancy are associated with less respiratory infections and asthma during childhood.

In a study published in the January 2011 issue of Pediatrics, the umbilical cord-blood level of vitamin D was evaluated at birth for 922 healthy newborns and these levels were compared to the incidence of respiratory infections, wheezing, and allergies over a 5 year period. The researchers discovered that low levels of vitamin D in cord-blood were associated with a higher risk of respiratory infections during the first months after birth and a higher risk of wheezing episodes throughout early childhood (Camargo, 2011). Twenty percent of the newborns in this study had a cord-blood level that indicated a deficiency of vitamin D (less than 25 nmol/L), and these babies had more infections and wheezing than infants with higher vitamin D levels.

Four previous studies published between 2006 and 2009 showed that the babies of mothers who ate foods high in vitamin D or took vitamin D supplements during pregnancy had a decreased incidence of wheezing and/or asthma (Erkkola, 2000; Miyake, 2010). This new study was the first to test the vitamin D level at birth and associate it with the occurrence of respiratory symptoms.

It was remarkable that a single low cord-blood level of vitamin D at birth would be associated with wheezing even several years later. The authors propose several possible reasons for this finding. Because vitamin D is essential for healthy immune system function, vitamin D may be necessary to initiate immune mechanisms while the baby is still in the womb or soon after birth.

Recommended supplements for pregnancy

Pregnant women should take a high quality prenatal vitamin/mineral supplement that contains folate. In addition during pregnancy it is important to take vitamin D, an omega-3 fatty acid supplement with DHA, and probiotics, all of which have proven to have positive health benefits for babies. Pregnant women should also have their vitamin D levels checked during pregnancy to ensure that they have achieved recommended levels of 70-100 nmol/L.

References

Camargo CA, et al. Cord-Blood 25-Hydroxyvitamin D Levels and Risk of Respiratory Infection, Wheezing, and Asthma. Pediatrics Vol. 127 No. 1 January 2011, pp. e180-e187.

Erkkola M, Kaila M, Nwaru BI, et al. Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children. Clin Exp Allergy. 2009;39(6):875-882.

Miyake Y, Sasaki S, Tanaka K, Hirota Y. Dairy food, calcium and vitamin D intake in pregnancy, and wheeze and eczema in infants. Eur Respir J. 2010;35(6):1228-1234.

Whitehouse, AJO, et al. Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive Development. Pediatrics 2012; 129:3 485-493; published ahead of print February 13, 2012, doi:10.1542/peds.2011-2644

 

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Vitamin D in the News

2011 March 10 by

As many of know by now the US Institute of Medicine (IOM) published a report this week stating that people do not need to take vitamin D supplements. They also warned that taking 10,000 IU or more per day could be toxic without producing any evidence to support that assertion. These recommendations fly in the face of many recent scientific studies that have shown the relationship of vitamin D deficiency to cancer, heart disease, diabetes, depression, and immune system problems. This evidence is so convincing that I advise all of my patients and my own family to take vitamin D3 supplements during the winter months, and to make sure their blood levels of vitamin D are adequate.

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Correct Vitamin D Dosage

2011 March 10 by

A new study published in the Feb 2011 issue of the Anticancer Research journal confirms that Vitamin D in the range of 4000-8000 IU is necessary for adults to maintain an adequate blood level of vitamin D to prevent chronic disease, including diabetes and cancer. This level of supplement intake contradicts the recent recommendation of the US Institute of Medicine, which would limit intake to much lower levels. That recommendation proved very controversial and many vitamin D experts complained that their advice was spurned by the recommendation committee. This study from the University of California, San Diego School of Medicine and Creighton University School of Medicine in Omaha shows the wisdom of the Vitamin D Council’s recommendation that adults take 5,000 IU of vitamin D3 per day.

My recommendation is that adults continue to take 5,000 IU Vitamin D3, children 2,000 IU, and infants 35 IU per pound of body weight (or 400-1,000 IU depending on weight).

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Teens and Bone Strength

2011 February 23 by

What factor is most important to ensure adequate bone density in teenage girls? When 80 young women were followed from age 12 to 22, the only factor that influenced bone density was exercise. Calcium intake and oral contraceptive use had no effect on bone strength. There may be other factors such as vitamin D levels from sun exposure and dietary sources, but the data pertaining to exercise was so dramatic that the study results are very convincing. What does this say to the dairy industry’s claims that milk creates strong bones? How should this study impact our thinking about the minimum daily intake of calcium for children? It should reassure those parents who limit dairy intake because of an allergy or sensitivity to milk, and it should make us less militant about the daily dose of calcium. It should also encourage parents to require an exercise program during early childhood and the teenage years.

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